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45388

Colonoscopy, flexible; with ablation of tumor(s), polyp(s), or other lesion(s) (includes pre- and post-dilation and guide wire passage, when performed)

Surgery Gastrointestinal System - Endoscopy 12.46 Total RVUs
Quick Reference
For colonoscopy with ablation of colonic lesions using alternative method

Relative Value Units (RVUs)

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Work RVU
4.60
Physician effort
PE RVU
7.40
Practice expense
MP RVU
0.46
Malpractice
Total RVU
12.46
Combined value
Dollar reimbursement rates vary by locality and payer. RVUs shown for relative comparison only.
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Clinical Information

When to Use

For colonoscopy with ablation of colonic lesions using alternative method

Time Requirement
30-50 minutes typical procedure time

Common Scenarios

Colonoscopy with cryoablation
Colonoscopy with radiofrequency ablation
Colonoscopy with alternative ablation method
Colonoscopy with lesion ablation
Colonoscopy with polyp ablation

Documentation Requirements

  • Indication for colonoscopy and ablation
  • Ablation method used
  • Location and size of ablated lesions
  • Number of lesions ablated
  • Post-ablation findings

Coding Guidelines

Common Modifiers

59 Distinct procedural service if performed with other procedures
52 Reduced services if procedure not completed
53 Discontinued procedure due to patient condition

Bundling Rules

  • Includes colonoscopy
  • Includes ablation therapy
  • Multiple lesions ablated bundled
  • Pre- and post-dilation included
  • Guide wire passage included

Exclusions

  • 45378 (colonoscopy diagnostic)
  • 45387 (colonoscopy with ablation, primary method)
  • 45385 (colonoscopy with polypectomy)
  • 45380 (colonoscopy with biopsy)

Coding Notes

No global period - diagnostic procedure
Alternative ablation method
Document ablation technique
Multiple lesions bundled

Clinical scenarios

Colonoscopy with cryoablation
Colonoscopy with cryoablation
When to use:For colonoscopy with ablation of colonic lesions using alternative method
  • Indication for colonoscopy and ablation
  • Ablation method used
  • Location and size of ablated lesions
Colonoscopy with radiofrequency ablation
Colonoscopy with radiofrequency ablation
When to use:For colonoscopy with ablation of colonic lesions using alternative method
  • Indication for colonoscopy and ablation
  • Ablation method used
  • Location and size of ablated lesions
Colonoscopy with alternative ablation method
Colonoscopy with alternative ablation method
When to use:For colonoscopy with ablation of colonic lesions using alternative method
  • Indication for colonoscopy and ablation
  • Ablation method used
  • Location and size of ablated lesions

Who are you?

Code Details

Code 45388
Category Surgery
Subcategory Gastrointestinal System - Endoscopy
Total RVUs 12.46

Medicare Pricing

PFS
2025 National Rate
$2,233.53
Facility
$258.45
Non-Facility
$2,233.53
RVU Breakdown
Work RVU:4.88PE RVU:63.54MP RVU:0.63Total RVU:69.05CF:$32.3465Global Days:000
OPPS Details
APC:5312Status:TCopayment:
Physician Fee Schedule: Medicare pays physicians based on Relative Value Units (RVUs) multiplied by a conversion factor.

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Frequently Asked Questions

What is CPT code 45388?

CPT 45388 is the billing code for "Colonoscopy, flexible; with ablation of tumor(s), polyp(s), or other lesion(s) (includes pre- and post-dilation and guide wire passage, when performed)". For colonoscopy with ablation of colonic lesions using alternative method

How much does Medicare pay for CPT 45388?

Medicare pays approximately $2233.53 for CPT 45388 (national average). Actual payment varies by geographic location due to GPCI adjustments. Hospital and commercial insurance rates are typically 2-4x higher than Medicare rates.

What are the RVUs for CPT 45388?

CPT 45388 has a total RVU of 12.46, broken down as: Work RVU 4.60, Practice Expense RVU 7.40, and Malpractice RVU 0.46. RVUs (Relative Value Units) determine Medicare reimbursement rates.

What documentation is required for CPT 45388?

Key documentation requirements for CPT 45388 include: Indication for colonoscopy and ablation; Ablation method used; Location and size of ablated lesions; Number of lesions ablated. Missing or incomplete documentation is a leading cause of claim denials for this code.

Can CPT 45388 be billed with other codes?

Bundling considerations for CPT 45388: Includes colonoscopy. Includes ablation therapy Use an NCCI bundling checker to verify specific code combinations before billing.

What modifiers are commonly used with CPT 45388?

Common modifiers for CPT 45388 include: 59 (Distinct procedural service if performed with other procedures), 52 (Reduced services if procedure not completed), 53 (Discontinued procedure due to patient condition). Modifiers indicate special circumstances and can affect reimbursement or prevent claim denials.

What is the time requirement for CPT 45388?

The typical time requirement for CPT 45388 is 30-50 minutes typical procedure time. Time-based codes require documentation of the actual time spent providing the service.

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