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45385

Colonoscopy, flexible; with removal of tumor(s), polyp(s), or other lesion(s) by snare technique

Surgery Gastrointestinal System - Endoscopy 11.75 Total RVUs
Quick Reference
For colonoscopy with removal of polyps or lesions using snare cautery technique

💬 Plain Language Explanation

What this means

This is a colonoscopy with removal of polyps - a procedure where a doctor examines your colon and removes polyps (small growths) that were found.

Why you might see this

This code is used when your colonoscopy included removing polyps. Polyps are small growths that can sometimes become cancerous, so removing them is important for preventing colon cancer.

Common context

Used when colonoscopy includes removing polyps, which is important for preventing colon cancer.

What to ask your provider

"'How many polyps were removed? What type were they? Do I need more frequent screenings?'"

Relative Value Units (RVUs)

Calculator →
Work RVU
4.50
Physician effort
PE RVU
6.80
Practice expense
MP RVU
0.45
Malpractice
Total RVU
11.75
Combined value
Dollar reimbursement rates vary by locality and payer. RVUs shown for relative comparison only.
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Clinical Information

When to Use

For colonoscopy with removal of polyps or lesions using snare cautery technique

Time Requirement
25-45 minutes typical procedure time

Common Scenarios

Colonoscopy with polypectomy for adenomatous polyps
Colonoscopy with removal of sessile polyps
Colonoscopy with removal of pedunculated polyps
Colonoscopy with piecemeal polypectomy
Colonoscopy with removal of hyperplastic polyps

Documentation Requirements

  • Indication for colonoscopy
  • Location, size, and type of each polyp removed
  • Polypectomy technique (snare cautery)
  • Number of polyps removed
  • Completeness of polypectomy

Coding Guidelines

Common Modifiers

59 Distinct procedural service if multiple polyps removed separately
33 Preventive service when performed for screening
22 Increased procedural services for large or complex polyps
52 Reduced services if procedure not completed

Bundling Rules

  • Includes colonoscopy
  • Includes polypectomy using snare technique
  • Multiple polyps removed same session bundled
  • Biopsy of polyp bundled when performed same session
  • Upper endoscopy coded separately if performed same session

Exclusions

  • 45378 (diagnostic colonoscopy)
  • 45380 (colonoscopy with biopsy only)
  • 45388 (colonoscopy with ablation of lesion)
  • 45390 (colonoscopy with endoscopic mucosal resection)

Coding Notes

No global period - diagnostic procedure
Snare technique required for this code
Piecemeal polypectomy included
Document polyp size and completeness of removal

Clinical scenarios

Colonoscopy with polypectomy for adenomatous polyps
Colonoscopy with polypectomy for adenomatous polyps
When to use:For colonoscopy with removal of polyps or lesions using snare cautery technique
  • Indication for colonoscopy
  • Location, size, and type of each polyp removed
  • Polypectomy technique (snare cautery)
Colonoscopy with removal of sessile polyps
Colonoscopy with removal of sessile polyps
When to use:For colonoscopy with removal of polyps or lesions using snare cautery technique
  • Indication for colonoscopy
  • Location, size, and type of each polyp removed
  • Polypectomy technique (snare cautery)
Colonoscopy with removal of pedunculated polyps
Colonoscopy with removal of pedunculated polyps
When to use:For colonoscopy with removal of polyps or lesions using snare cautery technique
  • Indication for colonoscopy
  • Location, size, and type of each polyp removed
  • Polypectomy technique (snare cautery)

Who are you?

Code Details

Code 45385
Category Surgery
Subcategory Gastrointestinal System - Endoscopy
Total RVUs 11.75

Medicare Pricing

PFS
2025 National Rate
$435.38
Facility
$242.92
Non-Facility
$435.38
RVU Breakdown
Work RVU:4.57PE RVU:8.33MP RVU:0.56Total RVU:13.46CF:$32.3465Global Days:000
OPPS Details
APC:5312Status:TCopayment:—
ⓘ Physician Fee Schedule: Medicare pays physicians based on Relative Value Units (RVUs) multiplied by a conversion factor.

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Frequently Asked Questions

What is CPT code 45385?

CPT 45385 is the billing code for "Colonoscopy, flexible; with removal of tumor(s), polyp(s), or other lesion(s) by snare technique". For colonoscopy with removal of polyps or lesions using snare cautery technique

How much does Medicare pay for CPT 45385?

Medicare pays approximately $435.38 for CPT 45385 (national average). Actual payment varies by geographic location due to GPCI adjustments. Hospital and commercial insurance rates are typically 2-4x higher than Medicare rates.

What are the RVUs for CPT 45385?

CPT 45385 has a total RVU of 11.75, broken down as: Work RVU 4.50, Practice Expense RVU 6.80, and Malpractice RVU 0.45. RVUs (Relative Value Units) determine Medicare reimbursement rates.

What documentation is required for CPT 45385?

Key documentation requirements for CPT 45385 include: Indication for colonoscopy; Location, size, and type of each polyp removed; Polypectomy technique (snare cautery); Number of polyps removed. Missing or incomplete documentation is a leading cause of claim denials for this code.

Can CPT 45385 be billed with other codes?

Bundling considerations for CPT 45385: Includes colonoscopy. Includes polypectomy using snare technique Use an NCCI bundling checker to verify specific code combinations before billing.

What modifiers are commonly used with CPT 45385?

Common modifiers for CPT 45385 include: 59 (Distinct procedural service if multiple polyps removed separately), 33 (Preventive service when performed for screening), 22 (Increased procedural services for large or complex polyps). Modifiers indicate special circumstances and can affect reimbursement or prevent claim denials.

What is the time requirement for CPT 45385?

The typical time requirement for CPT 45385 is 25-45 minutes typical procedure time. Time-based codes require documentation of the actual time spent providing the service.

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